Prof. Dr. Kashif Ali

92-21-111-922-478, Ext. 203
Building 172, First Floor

Prof. Dr. Kashif Ali

Head of Biosciences Department
Dean Faculty of Life Sciences
Head of Research Committee (SZABIST)

Brief Bio and Research Interest / Area of Research:

I was born and got my early education in Karachi and done my B.Sc. in Physiology, with Biochemistry and Microbiology and finish my M.Sc. in Biotechnology in 2005. In 2006, I started working as Junior Research Fellow at H.E.J. Research Institute of Chemistry where I focused on the enhanced production of valuable plant secondary metabolites using cell suspension cultures and chemical elicitors. In 2007, I got the Overseas Scholarship offered by Higher Education Commission of Pakistan for the Ph.D. studies at Leiden University, The Netherlands. I did my Ph.D. research on a project named Genomic Research Assisted breeding for Sustainable Production of quality grapes. In September 2011, I went to Qiagen (Germany) on Marie Curie Secondment (FP7 program) for my first Postdoc to work on metabolomics standardization. Later, I joined Leiden University for my second Postdoc where my work was on marine metabolomics. After that, I went to University of Florida as a Postdoctoral Associate to work on Vitamin B6 Metabolism in Maize.
In 2013, I joined SZABIST-Karachi as an Assistant Professor at Biosciences Department. During my tenure here, I have worked as a Program Manager for BS-Biosciences, BS-Biotechnology, MS-Biosciences, and Master of Science in Public Health Programs, and for the last five and a half years, I am working as a Head of Biosciences Department. Recently, I have been promoted to Professor and appointed as a Dean Faculty of Life Sciences. I am also in-charge SZABIST’s Center for Biosciences Research (SCBR) and also working on projects related to metabolic profiling of the various ornamental, fruit, and medicinal plants using NMR and other analytical platforms. My new interest is understanding Multi-Drug Resistance in Microbial Pathogens and developing methods to overcome this trait. So far, I have published more than 20 research articles in ISI indexed journals and contributed three book chapters in books published by international publishers.

Conference Presentations & Proceedings:

  • Inivited Speaker: 2nd International Chemistry Conference and Its Role in Sciences at University of Karachi (Pakistan), entitled as “Metabolomics and its application in health care”. 2019.
  • Inivited Speaker: International Conference on Applied Biosciences at Mohammad Ali Jinnah University, Karachi (Pakistan), entitled “NMR Metabolomics: a tool to identify metabolic differences in plants”. 2019.
  • Oral presentation at Microbiology Infectious Diseases and Health Safety at Swabi, (Pakistan) entitled as “Metabolic differentiation of grapevine cultivars using NMR and multivariate data analyses”. 2019.
  • Oral presentation at 1st Annual Health Research Conference at Islamabad (Pakistan) entitled as “Effects of ion channel blockers in combination with antibiotics against MRSA”. 2018.
  • Oral presentation at International Conference on Medical and Health Sciences at Barcelona (Spain) entitled as “Antimicrobial screening of Withania coagulans and Nigella sativa against clinical skin infection isolates”. 2018.
  • Oral presentation at 2nd Invention to Innovation Summit at Karachi (Pakistan) entitled as “Metabolomics: A holistic hope, or hype, or hot topic”. 2017.
  • Oral presentation at Future Trends in Phytochemistry in the Global Era of Agrifood and Health: A Young Scientists Meeting at Murcia (Spain) entitled as “Metabolic characterization of different grapevine cultivars using 1H NMR and multivariate data analyses”. 2009.
  • Oral presentation at Plant GEMs (Genomic European Meetings) at Lisbon (Portugal) entitled as “Transcriptional and metabolic profiling during ripening of Trincadeira grapes highlights cultivar specificities”. 2009.
  • Poster presentation at Plant GEMs (Genomic European Meetings) at Lisbon (Portugal) entitled as “Unraveling the defense response to Downy mildew:
  • Differences between resistant and susceptible grapevines”. 2009.

Honors & Awards:

  • Overseas Scholarship for Ph.D. Studies by HEC, Pakistan.
  • Marie Curie Fellowship under FP7 program of EU.
  • Included in the Directory of Most Productive Scientists of Pakistan (2017) by PCST.

Journal Articles – Peer Reviewed:

  • Bashir A, Soomro H, Farid N, Ali K, Kayani HA, Fatima K. 2020. Assessment and identification of cholesterol degrading probiotics. Science International (Lahore), 32, 107-111.
  • Fatima K, Farid N, Bashir A, Ali K. 2019. Qualitative and quantitative analysis of microbiology and anti-microbial resistance of Gharo water samples (Karachi-Pakistan; A case study. Science International (Lahore), 31, 857-860.
  • Mehmood S, Bashir A, Fatima K, Farid N, Ali K. 2018. Antimicrobial screening of Withania coagulans and Nigella sativa against clinical skin infection isolates. International Journal of Advances in Science, Engineering, and Technology, 6 Spl. Issue-1, 53-56.
  • Jahangir M, Mehmood Z, Saifullah, Bashir Q, Mehboob F, Ali K. 2016. Halal status of ingredients after physicochemical alteration (Istihalah). Trends in Food Science and Technology, 47, 78-81.
  • Saifullah, Azizuddin, Khan S, Ali K, Choudhary MI. 2014. Biotransformation of Dihydroepiandrosterone by cell suspension culture of Codiaeum variegatum. Chemistry of Natural Compounds, 4, 580-582.
  • Agudelo-Romero P, Ali K, Choi YH, Sousa L, Verpoorte R, Pais MS, Tiburcio A, Fortes AM. 2014. Perturbation of polyamine catabolism affects normal grape ripening of Trincadeira cultivar. Plant Physiology and Biochemistry, 74, 141-155.
  • Badar Z, Khan S, Saifullah, Ali K, Musharraf SG, Choudhary MI. 2013. In vitro and biotransformational studies of Aloe barbadensis Mill. Pakistan Journal of Botany, 46, 679-685.
  • Ali K, Iqbal M, Yuliana ND, Lee Y-J, Park S, Han S, Lee J-W, Lee H-S, Verpoorte R, Choi YH. 2013. Identification of bioactive metabolites against adenosine A1 receptor using NMR-based Metabolomics. Metabolomics, 9, 778-785.
  • Ali K*, Iqbal M*, Fortes AM, Pais MS, Korthout HAAJ, Verpoorte R, Choi YH. 2013. Red wines attenuate TNFα production in human histiocytic lymphoma cell line: An NMR spectroscopy and chemometrics based study. Food Chemistry, 141, 3124-3130.
  • Hasnain G, Roje S, Frelin O, Ellens KW, Ali K, Guan J-C, Garrett TJ, de CrécyLagard V, Gregory III JF, McCarty DR, Hanson AD. 2013. Identification and Characterization of the Missing Pyrimidine Reductase in the Plant Riboflavin Biosynthesis Pathway. Plant Physiology, 161, 48-56.
  • Ali K, Iqbal M, Korthout HAAJ, Maltese F, Fortes AM, Pais MS, Verpoorte R, Choi YH. 2012. NMR spectroscopy and chemometrics as a tool for anti-TNFα activity screening in crude extracts of grapes and other berries. Metabolomics, 8, 1148-1161.
  • Ali K, Maltese F, Figueiredo A, Rex M, Fortes AM, Zyprian E, Pais MS, Verpoorte R, Choi YH. 2012. Alterations in grapevine leaf metabolism upon inoculation with Plasmapora viticola in different time-points. Plant Science, 191-192, 100-107.
  • Gerardi C, Blando F, Mule G, Maltese F, Ali K, Verpoorte R. 2012. Metabolic characterization of Prunus cerasus L. and Prunus mahaleb L. fruits. Acta Horticulturae, 940, 361-368.
  • Fortes AM, Agudelo-Romero P, Silva MS, Ali K, Sousa L, Maltese F, Choi YH, Grimplet J, Martinez-Zapater JM, Verpoorte R, Pais MS. 2011. Transcript and metabolite analysis in Trincadeira cultivar reveals novel information regarding the dynamics of grape ripening. BMC Plant Biology, 11, 149.
  • Ali K, Maltese F, Fortes AM, Pais MS, Choi YH, Verpoorte R. 2011. Pre-analytical method for NMR-based grape metabolic fingerprinting and chemometrics. Analytica Chimica Acta, 703, 179-186.
  • Georgiev MI, Ali K, Alipieva K, Choi YH, Verpoorte R. 2011. Metabolic differentiations and classification of Verbascum species by NMR-based metabolomics. Phytochemistry, 72, 2045-2051.
  • Ali K, Maltese F, Toepfer R, Choi YH, Verpoorte R. 2011. Metabolic Characterization of Palatinate German white wines according to sensory attributes, varieties, and vintages using NMR spectroscopy and multivariate data analyses. Journal of Biomolecular NMR, 49, 255-266.
  • Ali K, Maltese F, Fortes AM, Pais MS, Choi YH, Verpoorte R. 2011. Monitoring biochemical changes during grape berry development in Portuguese cultivars by NMR spectroscopy. Food Chemistry, 124, 1760-1769.
  • Ali K, Maltese F, Choi YH, Verpoorte R. 2010. Metabolic constituents of grapevine and grape-derived products. Phytochemistry Reviews, 9, 357-378.
  • Ali K, Maltese F, Zyprian E, Rex M, Choi YH, Verpoorte R. 2009. NMR metabolic fingerprinting based grapevine metabolites associated with Downy mildew resistance. Journal of Agricultural and Food Chemistry, 57, 9599-9606.
  • Nasib A, Ali K, Khan S. 2008. In vitro propagation of Croton (Codiaeum variegatum). Pakistan Journal of Botany, 40, 99-104.
  • Nasib A, Ali K, Khan S. 2008. An optimized and improved method for the in vitro propagation of Kiwifruit (Actinidia deliciosa) using coconut water. Pakistan Journal of Botany, 40, 2355-2360.
  • Khan S, Naseeb S, Ali K. 2007. Callus induction, plant regeneration and acclimatization of African violet (Saintpaulia ionantha) using leaves as explants. Pakistan Journal of Botany, 39, 1263-1268.
  • Khan S, Naz S, Ali K, Zaidi S. 2006. Direct organogenesis of Kalanchoe tomentosa (Crassulaceae) from shoot tips. Pakistan Journal of Botany, 38, 977-981.